Crohn’s Disease

Posted by Alex

Crohn’s disease is a recurrent segmental inflammatory disorder that may affect the any location in the gastrointestinal tract from the mouth to the anus. Crohn’s disease is of unknown etiology. Fifty percent of patients have involvement of both the small intestine and colon, whereas one third have disease limited to their small intestine and the remaining 20% have inflammation in the colon only. Perianal lesions and inflammatory conditions involving the skin, eyes, joints, and liver are common. The transmural inflammatory process and variable anatomic extent of disease contribute to diverse clinical presentations with unpredictable spontaneous exacerbations and remissions.