Bronchioloalveolar Carcinoma in African Americans: PATIENTS AND METHODS

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This is a retrospective review of 19 cases of ВАС at Howard University Hospital between 1984 and 1999. Twenty-seven cases were identified during this period. Medical records of 19 patients were available for review. All the diagnoses had been determined by biopsy of specimens obtained by resection of lesion or transbronchial biopsy or CT-guided needle biopsy. The pathological reports were reviewed. Patient ages ranged from 49-89 years (average 63 years). All 15 men and four women were African Americans (Table 1). The cases were reviewed and the following information extracted: age at diagnosis, smoking history, occupation, previous pulmonary disease, symptoms, chest X-ray and CT scan, method of diagnosis, treatment, response to treatment, and survival time from the time of diagnosis. Institutional review board approval was obtained. The results of this study were statistically compared with the study by Feldman et al., which consisted of a mainly Caucasian population. Fisher exact test was used for statistical analysis. A p-value of <0.05 was considered statistically significant.

Table 1. Characteristics off Patients with ВАС
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Characteristics	Number of Patients (%) HUH (N=19)	Number of Patients (%) Mayo (N=25)*	P Value
Gender Male Female Age	15 (79%) 4 (21%)	15(60%) 10(40%)	0.21
Median (men) Median (women)	62 65	62 (for all patients)
Range (age) Men Women	44-89 54^84	43-79 (for all patients)
Smokers Current Previous None	15 (79%) 13 (68%) 2 (12%) 4(21%)	17(68%) 16 (64%) 1 (4%) 8 (32%)	0.51
Respiratory Diseases None Previous TB/COPD	17 (90%) 2(11%)	18 (72%) 7 (28%)	0.26
* Data from (Ref 24). By permission of Mayo Foundation.