A REPORT OF CLINICAL TRIAL CONDUCTED ON Тото OINTMENT: DISCUSSION

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The study has shown the efficacy and tolerability of Toto products (skin ointment and soap) in the management of common skin disorders. It also has a superior outcome as compared with sulfur ointment, a commonly used skin product. It is particularly efficacious in the management of skin conditions such as fungal and bacterial skin infections and scabies. The products are particularly effective in treating fungal infections and scabies. Such fungal skin infections include tinea cruris, corporis, pubis, and capitis. In treating tinea unguium and tinea pedis however, although the products have some effects, a definitive statement is difficult to make concerning the efficacy because of the few patients and duration of treatment. We suggest application of the ointment for a longer period in the management of tinea unguium and tinea pedis. Very few cases of dandruff and acne vulgaris were seen to allow for determination of the effects of the products, although the clinical trial recorded good effects on all the cases seen. Toto products were also effective in treating common bacterial skin infections such as folliculitis and septic spots caused especially by Staphylococcus aureus. The clinical trial has shown that there is an added advantage in combining Toto skin ointment and soap over and above those conferred by the individual agents, while treating fungal skin infections.

In none of the patients were any side effects observed. The absence of observable side effects showed that Toto ointment and soap are safe and acceptable. The twice-daily administration of Toto products was well accepted by all patients, thus reducing chances of non-compliance.

In conclusion, Toto products (ointment and soap) are effective in treating common skin conditions such as scabies; pityriasis versicolor, tinea capitis, tinea corporis, tinea pubis; bacterial skin infections due to Staphylococcus aureus such as folliculitis and septic spots. The combined products are particularly very effective for pityriasis versicolor, tinea corporis/ capitis and scabies.
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We recommend that efforts be made at comparing the product with other established, new generation antifungals and antibacterials on a long-term basis. Further studies are required to study the effects of the products on acne vulgaris (pimples) and dandruff.