Archive for February, 2011
Posted by James
SCC is an uncommon variant of SCC that was first described by Lever in 1947 as adenoacanthoma of the sweat glands. It was also known as adenoid , lobular SCC, or pseudoglandular SCC. As can be guessed by the name, it was previously thought to be a tumor of a sweat gland origin because of gland-like and solid epithelial prolifera¬tions extending into the dermis. However, A-SCC is now accepted as a distinct variant of SCC rather than a sweat gland tumor.
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Posted by James
An 82-year-old woman presented with an ery- thematous nodule on the left eyebrow with a 4-months-history. The patient was on medication for hypertension, but otherwise healthy without any other systemic diseases. She had a history of Mohs micrographic surgery for SCC on the right cheek 2 months previously. On examination, a non-inflamed slightly pruritic hyperkeratotic papule with tenderness was located on the left eyebrow (Fig. 1). Clinically prurigo nodularis, seborrheic keratosis, and SCC were suspected and then a shaving biopsy was performed for making the diagnosis.
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Posted by James
INTRODUCTION
Squamous cell carcinoma (SCC) is the second most common type of skin cancer and it has several subtypes that have varying clinical behavior and malignant potential. Acantholytic SCC (A-SCC) is the uncommon variant of SCC in which significant portions of the neoplastic proliferation show a pseudoglandular or tubular pattern. It resembles the structures of eccrine neoplasms, but it is negative for dPAS, CEA, and mucicarmine and it is only positive for EMA and cytokeratins (CKs). Read the rest of this entry »
Posted by James
Steatocystoma simplex is thought to originate from a nevoid malformation of the pilosebaceous duct junction and a non-heritable benign adnexal tumor. Brownstein first reported 30 cases of stea- tocystoma simplex as distinct clinical entity compared with steatocystoma multiplex as a counterpart disease in 1982.
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Posted by James
A 49-year-old man presented to our outpatient clinic with an asymptomatic papule on the right parietal scalp which had been present for about 1 year. The lesion had slowly enlarged a few months ago. The physical examination revealed a skin- colored, deep-seated, soft cystic mass on his right parietal scalp, 0.9 cm in diameter (Fig. 1). There was no remarkable family history of similar lesions. Clinically, the lesion appeared to be a trichilemmal cyst, and was completely excised. The histological examination revealed an undulating, configured cystic mass that was empty. The cyst was located in the dermis and the cystic walls were thin and lined by stratified squamous epithelium that lacked a stratum granulosum (Fig. 2A). The cyst contained eosinophilic hyalinized cuticle in the lumen and flattened sebaceous gland lobules close to the cystic wall (Fig. 2B). There have been no signs of recurrence or development of other cysts during the 4 month follow-up. Read the rest of this entry »
Posted by James
INTRODUCTION
Steatocystoma simplex, first described as a distinct entity by Brownstein in 1982, is an extremely rare benign adnexal tumor. The individual lesion of steatocystoma simplex is usually identical with that of steatocystoma multiplex, both clinically and histologically, but is characterized by solitary, non- heritable growth in adulthood. Steatocystoma simplex occurs predominantly on the face, but the incidence of steatocystoma simplex on the scalp is extremely low. Only three cases of steatocystoma simplex on the scalp have been reported worldwide. Read the rest of this entry »
Posted by James
Muscle herniation is defined as a protrusion of a portion of a muscle through a defect of the muscle fascia. The problem is mainly cosmetic, but the disorder may cause spontaneous pain, cramps or local tenderness. Muscle herniation is a relatively common complaint among athletes and it has been frequently reported in the orthopedic surgery literature. Most dermatologists are unfamiliar with this condition, and they are likely to consider it as a peculiar kind of tumor. For the case presented herein, the provisional diagnosis was angiolipomatosis, and an unnecessary skin biopsy was performed.
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