A Case of Acantholytic Squamous Cell Carcinoma

Posted by James

INTRODUCTION

Squamous cell carcinoma (SCC) is the second most common type of skin cancer and it has several subtypes that have varying clinical behavior and malignant potential. Acantholytic SCC (A-SCC) is the uncommon variant of SCC in which significant portions of the neoplastic proliferation show a pseudoglandular or tubular pattern. It resembles the structures of eccrine neoplasms, but it is negative for dPAS, CEA, and mucicarmine and it is only positive for EMA and cytokeratins (CKs). The prognosis of A-SCC remains controversial, but at present it is best considered to be SCC of an intermediate risk. Herein we report a case of acantholytic squamous cell carcinoma that occurred on the face of an 82-year-old woman. viagra 50 mg