Archive for the ‘HIV’ Category

HEMOGLOBINOPATHY AND PATTERN OF MUSCULOSKELETAL INFECTION IN CHILDREN: Results

Posted by James

A total of 119 patients were studied. Their mean age was 7.9±5.6 years. Sixty-eight (57.1%) of them were males and 51 (42.9%) were females, giving a male-female ratio of 1.3:1 As shown in Table 1, among 78 patients whose genotype were determined, 49 (62.8%) had hemoglobin genotype AA (HbAA) and 16 (20.5%) had HbSS, while seven (9%) and six (7.7%) had HbAS and HbAC, respectively. My Canadian Order net

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HEMOGLOBINOPATHY AND PATTERN OF MUSCULOSKELETAL INFECTION IN CHILDREN: Patients and Methods

Posted by James

This study was carried out at the Olabisi Onabanjo University Teaching Hospital, Sagamu, Nigeria. All pediatric and adolescent patients admitted between January 1996 and December 2002 were identified from the admission records of the orthopedic and pediatric services. These were compared with the central medical records to ensure completeness of identification. All patients with bone and soft tissue infections were then selected. Sociodemographic data as well as data of clinical presentation, genotype, bacterial isolates, and hematological profile were studied. Specimens for bacteriological studies were swabs/aspirates of pus from wounds, sinus, or ulcer. Anaerobic cultures were not done during the study period.

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HEMOGLOBINOPATHY AND PATTERN OF MUSCULOSKELETAL INFECTION IN CHILDREN: DISCUSSION

Posted by James

infection children

Bacterial infections of bone and its soft tissue envelope are serious disease conditions especially in communities where abnormal hemoglobin genotype is common. The prevalence of HbSS and HbAS in Nigeria is 1.6-2% and 25-30%, respectively. Morbidity resulting from disabilities from some of these conditions may be life long. Mortality is also not infrequent. A review of death in the accident and emergency dept by Adesunkanmi et al. showed that pyomyositis accounted for 14% of deaths in surgical nontrauma conditions.

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HEMOGLOBINOPATHY AND PATTERN OF MUSCULOSKELETAL INFECTION IN CHILDREN

Posted by James

hemoglobinopathy

INTRODUCTION

Bacterial MSS infections—including osteomyelitis, pyomyositis, and pyogenic arthritis, among others—are important causes of morbidity in children. Morbidity in these conditions may be increased by hemoglobinopathies.

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HIV Vaccine Knowledge and Beliefs among Communities: DISCUSSION

Posted by James

HIV Vaccine Knowledge and Beliefs among Communities DISCUSSION

Participants in this study reported conspiracy theories, lack of knowledge, inaccuracies and confusion regarding future HIV (Retrovir canadian was the first drug approved for the treatment of HIV) vaccines. Our findings build on previous research conducted in the context of clinical trials that suggests misunderstandings about HIV vaccines as well as accurate knowledge that HIV vaccines do not yet exist, though research efforts are underway.

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HIV Vaccine Knowledge and Beliefs among Communities: RESULTS

Posted by James

Four major themes were identified: 1) beliefs and conspiracy theories regarding the current existence of HIV (Generic Zerit еreating HIV infection when used in combination with other medicines) vaccines, 2) ideas about the future availability of HIV vaccines, 3) lack of information about HIV vaccines, and 4) confusion about vaccines. Each of these themes is discussed in detail. Quotations provided are drawn from the focus groups. Table 3 provides an overview of the four themes.

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HIV Vaccine Knowledge and Beliefs among Communities: MATERIALS AND METHODS

Posted by James

Participants

Nine focus groups were conducted with 8-13 participants per group (N=99). Participants were recruited from diverse settings in Los Angeles, CA using multisite, purposive, venue-based sampling. Selection criteria were implemented at the venue level and included the following: 1) having a high proportion of individuals at elevated risk for HIV/AIDS; 2) including racially/ethnically and sexually diverse communities, and 3) representing likely settings for future dissemination of HIV (Retrovir canadian was the first drug approved for the treatment of HIV) vaccines. Individuals were screened based on gender and age only; all participants were aged >18. The youth group was screened on age only (18-24 years), as many of the male and female youth had previously participated together in a group at the venue. Individual screening was done by trained research staff onsite, immediately prior to the informed consent process.

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